DosageFrom the trialsOct 2026

Sermorelin Dosage Chart: Trial Doses in mcg and mg

By Peptides Vietnam, published October 2026

Sermorelin dosage chart figures all come from published studies, not from one official number. The trials used a weight-based amount in children and a flat amount in older adults, and no adult dose is approved anywhere. The chart below lists each one with the people it was tested in and the study behind it.

The amounts the studies used

Children: 30 mcg/kg once a day under the skin, at bedtime

Older men: a flat 2 mg at night, or 0.5 to 1 mg twice a day

Pituitary test: 1 mcg/kg once, given into a vein

Disclaimer: these amounts come from published studies in the people named, not from a current approved label. They are shown to explain the research and the math, not as a dose to take. Sermorelin has no approved adult dose, and a licensed clinician makes any such call.

Clinic pages tend to give one generic number with nothing behind it. This chart ties every amount to its study, works the weight-based dose into plain math, and explains why no adult standard exists. For the compound itself, see the sermorelin overview.

Sources: Thorner et al. J Clin Endocrinol Metab 1996;81:1189. PMID 8772599. The main childhood growth study.; Vittone et al. Metabolism 1997;46:89. PMID 9005976. The six-week study in older men.; Prakash A, Goa K L. BioDrugs 1999;12:139. PMID 18031173. The market-era drug review.

What doses did the sermorelin trials use?

Here is every published regimen in one place. Each row names who was studied, how it was given, the amount, the timing, how long it ran, and the study you can open.

Published sermorelin regimens, by group. Amounts are study figures, not a recommendation. PubMed IDs read 23 October 2026.
Who was studied	Route	Amount used	Timing	Length	PMID
Children with growth hormone deficiency	Under the skin	30 mcg/kg once a day	At bedtime	Up to 12 months	8772599
Children, head to head with growth hormone	Infusion	30 or 60 mcg/kg a day	Continuous, 6 months	6 months	8329830
Children, long-term single daily dose	Under the skin	30 mcg/kg once a day	Daily	12 to 24 months	7735367
Diagnostic pituitary test	Into a vein	1 mcg/kg, single dose	One test	Single dose	7735368
Healthy older men, flat dose	Under the skin	2 mg once a night	At night	6 weeks	9005976
Older men, twice daily	Under the skin	0.5 mg and 1 mg twice a day	Twice daily	14 days each	1379256

Sources: Thorner et al. J Clin Endocrinol Metab 1996;81:1189. PMID 8772599. The main childhood growth study.; Chen et al. Acta Paediatr Suppl 1993;388:32. PMID 8329830. The childhood comparison with growth hormone.; Lanes and Carrillo. J Pediatr Endocrinol 1994;7:303. PMID 7735367. A multi-year childhood course.; A 1994 J Pediatr Endocrinol report. PMID 7735368. The single-dose pituitary test.; Vittone et al. Metabolism 1997;46:89. PMID 9005976. The six-week study in older men.; Corpas et al. J Clin Endocrinol Metab 1992;75:530. PMID 1379256. The two-week study in older men.

What does 30 mcg per kg work out to?

The childhood amount was tied to body weight. To turn a per-kilogram figure into a total, you multiply it by the weight. The table shows that plain math for the 30 mcg/kg daily amount, and for the higher 60 mcg/kg arm, at a few example weights.

The childhood per-kilogram amounts worked out at example body weights. Multiplication only, generated by script.
Body weight	At 30 mcg/kg a day	At 60 mcg/kg a day
15 kg	450 mcg	900 mcg
20 kg	600 mcg	1200 mcg
25 kg	750 mcg	1500 mcg
30 kg	900 mcg	1800 mcg
40 kg	1200 mcg	n/a
50 kg	1500 mcg	n/a

How to read it: a 20 kg child at 30 mcg/kg works out to 600 mcg a day, because 30 times 20 is 600. The 60 mcg/kg column was only an arm in one childhood trial, so the larger weights are left blank.

Disclaimer: this is arithmetic that turns a study amount into milligrams or syringe units. It is not a dose for anyone, and a licensed clinician makes any dose decision.

How many syringe units is a sermorelin dose?

Units depend on how much water you mix into the vial. The table turns the flat adult amounts into units on a U-100 insulin syringe, for a 5 mg and a 10 mg vial at two water volumes. The total in the vial does not change with the water; only the units for a given amount do.

Syringe units for flat sermorelin amounts, by vial and water volume. U-100 units, generated by script.
Vial	Water	Strength	0.5 mg	1 mg	2 mg
5 mg	1 mL	5000 mcg/mL	10 units	20 units	40 units
5 mg	2 mL	2500 mcg/mL	20 units	40 units	80 units
10 mg	1 mL	10000 mcg/mL	5 units	10 units	20 units
10 mg	2 mL	5000 mcg/mL	10 units	20 units	40 units

For any other vial or amount, the peptide reconstitution calculator runs the same steps as you type.

Disclaimer: this is arithmetic that turns a study amount into milligrams or syringe units. It is not a dose for anyone, and a licensed clinician makes any dose decision.

Sources: The U-100 insulin syringe standard, where one full millilitre reads as 100 units.; Vittone et al. Metabolism 1997;46:89. PMID 9005976. The six-week study in older men.; Corpas et al. J Clin Endocrinol Metab 1992;75:530. PMID 1379256. The two-week study in older men.

Why is there no set adult dose?

Most of the strong evidence is in children, where the amount was tied to weight for a medical reason. The adult studies were small and short, and they measured hormone levels rather than any body-shape result. So there was never an adult amount proven to do a specific job.

On top of that, there is no current approved label. The Geref brand was pulled in 2009, and a 2013 FDA notice ties the exit to the maker stopping, not to safety or results. With no label, no official adult amount exists to copy.

That is why this page is a record of trial amounts, not a plan. For what the studies reported as harms, see the sermorelin side effects guide.

Sources: Vittone et al. Metabolism 1997;46:89. PMID 9005976. The six-week study in older men.; Corpas et al. J Clin Endocrinol Metab 1992;75:530. PMID 1379256. The two-week study in older men.; A US FDA Federal Register notice of 4 March 2013, on the Geref product and its exit from sale.

What about timing and how long it ran?

Timing was mostly at night. The childhood dose was given at bedtime to line up with the body clock, and the flat adult amount was given once nightly. The twice-daily adult study split the amount across the day instead.

Length ran from a single test dose to a full year in children. The chart above lists the length next to each amount, so you can see how short most of the adult work really was.

Sources: Prakash A, Goa K L. BioDrugs 1999;12:139. PMID 18031173. The market-era drug review.; Vittone et al. Metabolism 1997;46:89. PMID 9005976. The six-week study in older men.; Corpas et al. J Clin Endocrinol Metab 1992;75:530. PMID 1379256. The two-week study in older men.

Common questions

When is the best time of day for a sermorelin injection?+

The childhood trials gave it at bedtime, and a market-era drug review notes the same bedtime habit. The idea was to work with the natural nighttime release of growth hormone. That is what the studies did, not a schedule set for any reader.

Is 3 months of sermorelin enough?+

There is no set adult course, so there is no fixed answer. The trials ran from two weeks to a year, and in children the growth gain was largest around six months. In the studies, the effect faded once the shots stopped, so nothing carried on after treatment ended.

Is sermorelin the same as HGH?+

No. Sermorelin asks the pituitary to release its own growth hormone, while HGH is growth hormone added from outside. In a head to head childhood trial, growth hormone grew children faster than the peptide did. They are different treatments with different amounts.

Is there a sermorelin dose for muscle growth?+

No trial set one. The studies looked at childhood growth and at hormone levels in older adults, not at muscle building in healthy people. Any muscle-growth number you see online is a marketing figure, not a trial result, so this chart does not list one.

What did the adult studies use?+

Two main patterns appear in the chart above: a flat nightly dose in older men for six weeks, and a smaller twice-daily dose for two weeks. Both measured hormones, and the figures sit in the table with their trials, inside the disclaimer that frames them.

Keep reading on sermorelin

Sermorelin Overview

Evidence, status and background

Sermorelin Side Effects

Each effect tied to its trial

Reconstitution Calculator

Type a vial and water volume

Tesamorelin Calculator

Units for the related releaser

CJC-1295 vs Sermorelin

Two GHRH cousins compared

HGH vs Peptides

Releasers next to growth hormone

This dosage chart from Peptides Vietnam lists amounts from published sermorelin studies so you can see the research and the math. Read it as background, not medical advice; it sets no amount for any reader to use. Sermorelin carries no current approved label.