Retatrutide Weight Loss Calculator

It estimates a weight loss timeline from your own stats. It pairs the Mifflin-St Jeor equation for daily energy burn with our own conservative assumption of about 0.5 percent of body weight lost per week, which is not a figure the published Phase 2 Retatrutide trial reported. That trial is cited on this page as context only. You enter your weight, goal weight, height, age, activity, calorie target, and protein level, and it projects body weight at 12, 24, and 48 weeks, your BMI, your daily energy burn (TDEE), and how those numbers shift when a calorie deficit is added on top. The outputs are projections for education, not medical instructions, and individual results vary.

Retatrutide ships as a freeze-dried (lyophilized) powder that has to be dissolved in liquid before it can be measured. Reconstitution is that mixing step: adding bacteriostatic water to the vial turns the powder into a solution at a known concentration, which is what lets a dose be drawn accurately. The amount of water you add changes the concentration and the volume you draw, not the total amount of peptide in the vial. Our peptide reconstitution calculator handles that concentration math.

They are estimates, not guarantees. The model pairs the Mifflin-St Jeor equation for energy burn with a deliberately conservative drug-effect assumption of about 0.5 percent of body weight per week, applied on top of whatever calorie deficit your inputs produce. That weekly rate is our own conservative assumption and not a figure the trial reported: the Phase 2 trial reported a 24.2 percent mean weight loss at the highest dose over 48 weeks, under trial conditions that included a supervised lifestyle programme. Your real numbers depend on diet, sleep, training, genetics, and consistency, so treat the timeline as a planning reference rather than a promise.

Rapid weight loss can cost lean mass alongside fat. Research on weight loss generally reports that higher protein intake and resistance training are associated with better preservation of lean mass during a calorie deficit. That is a direction the research supports, not a number, so this calculator gives you a daily protein target scaled to your body weight and does not put a personal muscle retention percentage on the screen.

It records what the 12mg group of the published Phase 2 trial actually did. In that trial, groups assigned 4mg or higher started at either 2mg or 4mg once weekly, followed by gradual dose escalation every 4 weeks for up to 12 weeks. The 12mg group was the arm that started at 2mg, so it reached 12mg from week 13. It is shown as trial context only. It is not a prescription or a personal protocol, and decisions about whether a compound is appropriate for you, and at what dose, belong with a qualified clinician who knows your history.