CJC-1295 (No DAC)

Mod GRF 1-29. Short-acting GHRH analogue for pulsatile GH release. The ideal partner for Ipamorelin.

Last updated: May 2026

What is CJC-1295 (No DAC)?

CJC-1295 without DAC (also known as Modified GRF 1-29 or Mod GRF 1-29) is a truncated, stabilized form of GHRH (Growth Hormone Releasing Hormone) with a half-life of approximately 30 minutes. Unlike CJC-1295 with DAC, it does not bind to albumin and is cleared relatively quickly from the body. Browse the full peptide library for related GH compounds.

This shorter half-life means it produces a sharp, pulsatile GH release that more closely mimics the natural pattern of GH secretion, a burst every few hours. When combined with Ipamorelin (which activates the GH secretagogue receptor), the two peptides work synergistically to produce significantly higher and more sustained GH pulses than either can achieve alone.

CJC-1295 (no DAC) + Ipamorelin is considered the gold-standard GH protocol in the peptide community. It's favored for its physiological GH pattern, excellent tolerability, and the ability to time doses strategically (pre-sleep, pre-workout). For FDA-approved visceral fat reduction specifically, see tesamorelin.

How It Works

GHRH Mimicry: Binds to GHRH receptors in the pituitary, signaling it to release stored GH. Acts like a "command" signal.

Short Half-Life Advantage: The ~30 minute half-life means each dose creates a clean GH pulse that rises and falls naturally, mimicking physiological GH patterns rather than creating a sustained bleed.

Ipamorelin Synergy: While CJC (no DAC) signals the pituitary to release GH, Ipamorelin amplifies that signal via the ghrelin receptor. Combined, GH output is substantially higher than either alone.

Benefits

Natural pulsatile GH release pattern
Excellent synergy with Ipamorelin (gold-standard stack)
Strategic timing possible (sleep, workout)
Less water retention vs CJC with DAC
Improved sleep, recovery, and body composition
Lower risk of pituitary desensitization vs DAC version

Dosing Protocol

Phase	Dose	Frequency	Duration
CJC/Ipa Stack	100mcg CJC + 100mcg Ipa	1–3x daily	12 weeks
Pre-Sleep Dose	100mcg each	Before bed (fasted)	Ongoing
Cycle	100mcg each	2x daily	12 weeks on, 4 off

Always start at the lowest effective dose and titrate up gradually.

Side Effects

Common

⚠Mild water retention (less than DAC version)
⚠Tingling in hands/feet
⚠Mild hunger increase
⚠Headache in first week

Rare

•Hypoglycemia
•Pituitary desensitization with very high doses

Who Should NOT Use CJC-1295 (No DAC)

✕Active cancer
✕Diabetic retinopathy
✕Pregnancy or breastfeeding

What to Expect

Week 1–2

Improved sleep quality is often the first sign. Mild water retention possible.

Week 3–6

Faster recovery. Better body composition. Skin quality improving.

Month 2–3

Clear anabolic and fat-loss effects when combined with training and diet.

Month 3+

Complete the cycle and take a 4 week break before repeating.

Notes from Ho Chi Minh City

The CJC no-DAC plus Ipamorelin stack is what I keep on standby year-round and run in 12-week cycles. The pre-sleep shot at 100mcg of each, fasted at least 3 hours after dinner, is non-negotiable; the GH pulse during slow-wave sleep is where most of the recovery and skin-quality benefit comes from in my experience. I switched from CJC with DAC to no-DAC about 18 months ago because the water retention from DAC was making my training BJJ in HCMC heat noticeably uncomfortable, and the no-DAC version gives a cleaner pulse without that bloat. I keep the reconstituted vial in the fridge and use bacteriostatic water from a verified supplier; sterile water alone gives the peptide a 7-day shelf life which is too short to be practical.

FAQ

Q: Do I need to use CJC (no DAC) and Ipamorelin together?

A: You can use either alone, but the combination is significantly more effective. They work through different receptors (GHRH vs ghrelin) and the synergy produces substantially higher GH output. The stack is widely considered the minimum effective approach.

Q: How many times per day should I dose?

A: 1–3 times per day. Most users dose once before sleep for recovery and sleep benefits. Advanced users add a pre-workout dose. 3x per day is reserved for those with specific body composition goals. Always dose fasted because insulin blunts GH release. Source from the community-verified supplier list.

Where to Get CJC-1295 (No DAC) in Vietnam

See our community-verified supplier list with COA verification and cold-chain shipping to Vietnam.

View Supply Index

Related Peptides

Ipamorelin CJC-1295 (with DAC)Tesamorelin MOTS-c

Research & Sources

Effects of an analog of growth hormone-releasing factor on GH secretion in normal human subjects · Jette L, Leger R, Thibaudeau K, et al. · Endocrinology (2005) PMID: 15919742
Pharmacokinetic and pharmacodynamic data underlying the short half-life advantage of Mod GRF 1-29.
Synergy between GHRH and a GH-releasing peptide for stimulation of GH release in humans · Bowers CY, Granda R, Mohan S, Kuipers J, Baylink D, Veldhuis JD · Journal of Clinical Endocrinology and Metabolism (2004) PMID: 15292313
Demonstrates the synergistic GH release when GHRH analogues are combined with GH secretagogues like ipamorelin.
Pulsatile growth hormone secretion in normal man · Hartman ML, Veldhuis JD, Thorner MO · Hormone Research (1993) PMID: 8330775
Defines the natural pulsatile GH pattern that the CJC no-DAC plus ipamorelin protocol attempts to replicate.
Long-acting albumin-binding GHRH analogues: insights into the design of CJC-1295 · Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA · Journal of Clinical Endocrinology and Metabolism (2006) PMID: 16380436
Compares DAC vs non-DAC CJC-1295 forms to clarify the trade-off between sustained vs pulsatile GH release.

Important Disclaimer

Educational content only. Not medical advice. Peptides discussed on this page are not approved by Vietnam’s Ministry of Health (Bộ Y Tế) or the Drug Administration of Vietnam (DAV) for the indications described. Research peptides are not stocked at Long Châu, Pharmacity, or any retail pharmacy in Vietnam. Consult a licensed physician before any use.