CJC-1295 / Ipamorelin Protocol
The gold-standard growth hormone stack. CJC-1295 provides sustained GH release while Ipamorelin delivers a clean, pulsatile GH spike — together they synergize for superior body composition, recovery, and anti-aging results.
Why Stack These Two?
CJC-1295 (GHRH)
A Growth Hormone Releasing Hormone (GHRH) analogue that elevates baseline GH secretion by amplifying the pituitary's GH output over several hours. Provides the "foundation" of elevated GH throughout the day.
Ipamorelin (GHRP)
A Growth Hormone Releasing Peptide (GHRP) that triggers a clean, strong GH pulse from the pituitary without significantly raising cortisol or prolactin. Provides the "spike" on top of CJC-1295's baseline elevation.
Synergistic Effect: GHRH analogues (CJC-1295) and GHRPs (Ipamorelin) work on different receptors and by different mechanisms — combining them produces a GH pulse significantly larger than either alone. Studies show the combined effect is roughly 3–5x greater than monotherapy with either peptide.
Dosing Protocol
| Time | Peptide | Dose | Notes |
|---|---|---|---|
| Before bed (fasted 2+ hrs) | CJC-1295 no-DAC | 100mcg | Same syringe as Ipamorelin |
| Before bed (fasted 2+ hrs) | Ipamorelin | 200mcg | Mix with CJC in same syringe |
| Optional: Pre-workout (fasted) | CJC-1295 no-DAC | 100mcg | Second pulse for advanced users |
| Optional: Pre-workout (fasted) | Ipamorelin | 200mcg | Second pulse for advanced users |
Always inject fasted (minimum 2 hours after eating, 30–60 minutes before eating). Food raises insulin, which blunts GH release.
Cycle Structure
Single bedtime injection only. 1x CJC + 1x Ipamorelin per day. Assess results, sleep quality, body composition changes.
Bedtime injection required, optional second pre-workout pulse. Expect more pronounced body composition changes.
Two daily injections. Some users run longer cycles with lab monitoring of IGF-1 levels.
If using CJC-1295 with DAC instead of no-DAC: inject CJC once or twice weekly (its half-life is ~8 days). Ipamorelin still injected daily at bedtime.
What to Expect
Week 1–2
Improved sleep quality and deeper sleep cycles. Many users report vivid dreams. Energy begins to improve.
Week 3–4
Mild body composition changes become noticeable — slight muscle fullness and reduction in soft fat, particularly around midsection.
Month 2
More significant body composition changes. Muscle definition improves, fat decreases. Recovery from training accelerates noticeably.
Month 3+
Skin quality improvements, reduced joint soreness, improved overall body composition. IGF-1 levels elevated if tested.
Key Tips
Note: GH-related peptides may increase IGF-1 levels. Those with a history of cancer should consult an oncologist before use, as elevated IGF-1 may promote cancer cell growth in susceptible individuals.