CJC-1295 Reconstitution Calculator
Turn a target dose you already have into the exact injection volume and insulin syringe units for your vial. The arithmetic works the same for DAC and no-DAC, and the calculator never picks a dose for you.
Read this before you use the tool: there is no established human dose for CJC-1295 to fall back on. No regulator has approved it, anywhere, so no label sets a figure, and no human dosing regimen for body composition or wellness has been established in the published literature. The only human trial was investigational, weight-based, on the DAC form, and measured hormone levels rather than any physique outcome. The no-DAC form has no published human dosing at all. Every number this page produces is arithmetic on a figure you supplied, not a dose anyone established.
Most people who search for a CJC-1295 dosage calculator want a tool that tells them what to inject, but a calculator cannot make that decision, and with no established human dose there is nothing for it to copy. What number to enter, and whether to use CJC-1295 at all, is a decision for a licensed prescriber who knows your history. This tool handles only the arithmetic: once you already have a target number from your own protocol source or supplier, it converts that number into a concentration, a volume in millilitres, and U-100 syringe units. CJC-1295 with DAC and CJC-1295 without DAC are pharmacologically different. Their vial math is the same, and nothing else on this page treats them as interchangeable.
Enter your own numbers
The dose control starts at zero, and nothing is calculated until you move it. There is no established human dose for CJC-1295 that this calculator could start you on. Drag the slider to the figure your own protocol source specifies.
This selection labels the result only. The forms are pharmacologically different, but the reconstitution formula is identical.
Target dose from your protocol source or supplier. The slider starts at zero because no figure shown here would be a recommended, standard, or safe dose. Drag it to your own number and the math updates as you move it.
What the evidence and the community report
These are amounts recorded in published studies, registered trials, and named community sources, not recommendations. The Who column says whether a figure came from people in a study or from self-reported practice, and the Ref column points to the numbered entry in Sources at the bottom of this page.
A. Approved label doses
None. No regulator has approved CJC-1295 in either form, so no label sets a figure and DailyMed returns no product label.
B. Amounts administered in published studies
All rows are the DAC form, because there is no published human dosing study of CJC-1295 without DAC (modified GRF 1-29).
| Amount | Schedule | Route | Who | Ref |
|---|---|---|---|---|
| 30 and 60 microgram/kg | single dose, four ascending | subcutaneous | human, DAC, n not stated | [1] |
| 60 or 90 microgram/kg | single injection | subcutaneous | human, DAC, n not stated | [6] |
| not disclosed in the registry record | 12 weeks of administration | not stated | human, DAC, n = 120 enrolled | [7] |
| not stated in the abstract | single injection, sampled one week after | subcutaneous | human, DAC, n = 11 | [8] |
Per-kg figures are stated per kilogram of body weight exactly as the source states them, and are not converted here. In the first row the other two of the four ascending amounts are not stated in the abstract.
C. Community reported practice
Self-reported, not peer reviewed, published by a commercial source with a provider directory and referral model, and nobody verified these amounts were taken or were safe.
| Amount | Schedule | Route | Who | Ref |
|---|---|---|---|---|
| 1 to 2 mg | 1 to 2 times per week | subcutaneous | self-reported, DAC | [9] |
| 100 microgram | 1 to 3 times per day | subcutaneous | self-reported, no DAC | [9] |
| typically 100 microgram of each when paired with ipamorelin | not stated | subcutaneous | self-reported, no DAC | [9] |
Disclaimer: no figure here is a recommendation, per-kg amounts never convert into a human dose, and what to take is a decision for a licensed prescriber who knows your history.
Two arithmetic illustrations
Both cards use the same 1000 mcg figure, a round number chosen so the arithmetic is easy to follow and the effect of water volume stays visible. It is not a recommendation, and it is not a dose to take. Use the figure your own protocol source specifies. Both calculations work identically for CJC-1295 with DAC and without DAC.
Example A: 5 mg vial with 2 mL
Math illustration, not a dose to take. The concentration is 5 / 2 = 2.5 mg/mL, or 2500 mcg/mL. A 1000 mcg target gives 1000 / 2500 = 0.4 mL, which is 40 units on a U-100 syringe. The vial contains 5000 / 1000 = 5 illustrative draws.
Example B: 5 mg vial with 1 mL
Math illustration, not a dose to take. The concentration is 5 / 1 = 5 mg/mL, or 5000 mcg/mL. A 1000 mcg target gives 1000 / 5000 = 0.2 mL, which is 20 units on a U-100 syringe. The vial still contains 5000 / 1000 = 5 illustrative draws.
Halving the water doubles the concentration and halves the draw volume. It does not change the amount of peptide in the vial or the number of equal draws in this illustration.
What this calculator does, and what it will not do
A reconstitution calculator answers a mechanical question. The amount in the vial divided by the water volume gives the concentration. A target number divided by that concentration gives the matching liquid volume. There is no clinical judgment in those divisions.
The calculator will not choose a form, dose, timing, or schedule. The target number is something you bring to the calculator, not something it gives you. If you do not have a number from a licensed prescriber or a protocol source you trust, no calculation on this page can supply one.
The reconstitution formula
concentration = vial amount / water added
volume = target amount / concentration
U-100 units = volume in mL x 100
These inputs are quantities, not pharmacology. That is why the same formula handles either form while the form selector keeps the vial label visible.
Picking the BAC water volume
The water input does not change how much peptide is in the vial. It changes the concentration and therefore the liquid volume for the target number you enter. A 5 mg vial with 1 mL is twice as concentrated as the same vial with 2 mL, so the same target produces half the draw volume. The slider recomputes the result immediately so you can compare the arithmetic against the written instructions for your vial.
Reading the insulin syringe
The calculator uses the U-100 conversion:
1 unit = 0.01 mL
100 units = 1 mL = full 1 mL barrel
A result of 0.5 mL is 50 units, and a result of 0.25 mL is 25 units. The calculator shows both formats and checks the volume against the selected 0.3 mL, 0.5 mL, or 1.0 mL barrel capacity.
Keep DAC and no-DAC separate
The human trial and the earlier animal and in-vitro mechanism paper apply to CJC-1295 with DAC (PMIDs: 16352683 and 15817669). Their findings cannot be transferred to CJC-1295 without DAC.
The calculator shares only the vial arithmetic because that formula uses quantity, water volume, and the target number you enter. It does not use DAC findings for no-DAC, select a form, or translate either form into a schedule.
For compound-specific information, read the CJC-1295 with DAC profile and the CJC-1295 without DAC profile. They are separate references because the two forms must not be conflated.
Evidence boundary
The only human trial among the first five sources listed below applies to CJC-1295 with DAC (PMID: 16352683). The animal and in-vitro mechanism paper is also DAC-specific (PMID: 15817669). Neither paper gives this calculator a basis for selecting a personal target number, and neither can supply evidence for the no-DAC form.
The 2026 review names both forms and sorts them by the evidence available for each (PMID: 42395176). The remaining papers are analytical detection methods (PMIDs: 37806509 and 21871962), not dose-selection studies. None of those five sources turns a calculator output into a recommendation.
Sources
1. Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006 Mar;91(3):799-805. PMID: 16352683. DOI: 10.1210/jc.2005-1536.
2. Jetté L, Léger R, Thibaudeau K, Benquet C, Robitaille M, Pellerin I, et al. Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog. Endocrinology. 2005 Jul;146(7):3052-8. PMID: 15817669. DOI: 10.1210/en.2004-1286.
3. Dominikowski A, Rękoś Z, Olejarz M, Szczepanek-Parulska E, Domin R, RuchaŁa M. The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration. Front Endocrinol (Lausanne). 2026;17:1822475. PMID: 42395176. DOI: 10.3389/fendo.2026.1822475.
4. Cristea CD, Radu M, Toboc A, Stan C, David V. Cationic exchange SPE combined with triple quadrupole UHPLC-MS/MS for detection of GHRHs in urine samples. Anal Biochem. 2023 Dec 1;682:115336. PMID: 37806509. DOI: 10.1016/j.ab.2023.115336.
5. Thomas A, Schänzer W, Delahaut P, Thevis M. Immunoaffinity purification of peptide hormones prior to liquid chromatography-mass spectrometry in doping controls. Methods. 2012 Feb;56(2):230-5. PMID: 21871962. DOI: 10.1016/j.ymeth.2011.08.009.
6. Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. J Clin Endocrinol Metab, 2007 (PubMed pubdate lists 2006). Form: with DAC. Route: subcutaneous. Subjects: healthy men aged 20 to 40. PMID: 17018654.
7. NCT00267527. ClinicalTrials.gov registry record. Sponsor ConjuChem, phase 2, status TERMINATED, 12 weeks of administration. Form: with DAC. Route: not stated in the record fetched. Population: HIV infected patients with HIV associated visceral obesity, 120 enrolled per the record. Amount not disclosed in the registry record.
8. Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects. Growth Horm IGF Res. Form: with DAC. Route: subcutaneous. Subjects: healthy young adult men, n = 11, sampled before and one week after a single injection. Graded plausible rather than confirmed. PMID: 19386527.
9. PeptideProbe. CJC-1295 Dosage Chart: With DAC vs No DAC. Self-reported community practice, not peer reviewed, published by a commercial source that operates a provider directory and referral model. Fetched 2026-08-04. https://peptideprobe.com/dosage-charts/cjc-1295
Frequently asked questions
Is there a standard CJC-1295 dose?
No. There is no established human dose for CJC-1295. It is not approved by any regulator anywhere, so no label sets a figure, and no human dosing regimen for body composition or wellness has been established in the published literature. The only human trial used weight-based dosing of the DAC form in an investigational setting for hormone-level endpoints, which is not personal guidance, and the no-DAC form has no published human dosing at all. The dose control starts at zero and only you can set it, so the calculator never puts a number in front of you.
How do CJC-1295 DAC and no-DAC differ?
They are pharmacologically different forms, and findings from the DAC studies cannot be transferred to the no-DAC form. That distinction does not enter the reconstitution formula. Vial amount, water volume, and the target number you supply are the only calculator inputs. The form selector keeps the vial label visible without changing the math.
Do I mix DAC and no-DAC CJC-1295 differently?
The reconstitution arithmetic is the same for both. Vial size divided by the water added gives the concentration, and the target number divided by that concentration gives the draw volume. The two forms are not interchangeable, so confirm which form is in the vial and label it clearly. The shared calculation does not make them the same compound.
How do I use this calculator for my own target dose?
The dose control starts at zero and the results stay blank until you move it. Drag the slider to the figure your own protocol source or supplier specifies, in mcg or mg, and the calculator returns the volume, U-100 syringe units, and how many such draws the vial contains. It does not assess or recommend the number.
How much BAC water do I add to a 5 mg CJC-1295 vial?
The calculator does not prescribe one water volume. A 5 mg vial in 2 mL gives a concentration of 2.5 mg/mL. The same vial in 1 mL gives 5 mg/mL, so the same target number produces half the draw volume at the higher concentration. Water volume changes the concentration and syringe reading, not the total peptide in the vial. The arithmetic is identical for DAC and no-DAC.
Why does changing BAC water change the syringe reading?
The peptide amount in the vial stays fixed. More water lowers the concentration, so the same target number produces a larger liquid volume. Less water raises the concentration, so the same target number produces a smaller liquid volume. The calculator updates both millilitres and U-100 units when the water slider moves.
How do I read the insulin syringe units?
On a U-100 insulin syringe, 1 unit equals 0.01 mL and 100 units equals 1 mL. The calculator multiplies the liquid volume in millilitres by 100 and shows that result as syringe units. It also checks the result against the capacity of the syringe you selected.
Is this calculator medical advice?
No. It is harm reduction education. It performs reconstitution arithmetic on numbers you supply. It does not diagnose, prescribe, or tell you what dose or schedule to use. Cross-check the result with your protocol source, supplier instructions, and where possible a qualified clinician.
This is harm reduction education, not medical advice
This calculator is for educational use. It converts a target number you already have into a volume and syringe reading. It does not choose a dose. Peptide protocols vary between individuals and compounds. Cross-check the result with your protocol source, supplier instructions, and where possible a qualified clinician.